Satellite Glial Cell Markers

The p75ntr cells were also positive for the pan glial cell markers s100 nestin and sox10 but negative for fibroblast and macrophage markers.

Satellite glial cell markers.

Current topics and past controversies. Garden ga and campbell bm 2016 glial biomarkers in human central nervous system disease. Glutamine synthetase glial fibrillary acidic protein and s100β. After subculture cells were identified by immunofluorescence labeling for three satellite glial cell specific markers.

Ginhoux f and prinz m 2015 origin of microglia. In the drgs the cell bodies of these primary afferents are anatomically surrounded by satellite glial cells sgcs forming distinct functional units. Glial cell markers glial cells commonly called neuroglia or simply glia are non neuronal cells that provide support and nutrition maintain homeostasis form myelin and participate in signal transmission in the nervous system in. Current topics and past controversies.

Moreover they were negative for a satellite glial cell marker inwardly rectifying potassium channel kir4 1 as well as a nonmyelinating schwann cell marker glial fibrillary acidic protein. Sgcs may be identified by the expression of several glial markers such as glutamine synthetase gs and s100β. From studies on rats and mice researchers have found that satellite glial cells express many neurotransmitter receptors such as muscarinic acetylcholine and erythropoietin receptors. Cultured cells expressed glutamine synthetase glial fibrillary acidic protein and s100β suggesting they are satellite glial cells with a purity of 95.

Here we developed the cellmarker databases aiming to provide a comprehensive and accurate resource of cell markers for various cell types in tissues of human and mouse. Overview for cellmarker by manually curating over 100 000 published papers 4 124 entries including the cell marker information tissue type cell type cancer information and source were recorded. In order to differentiate between sgcs and other glial cells researchers have used markers to identify which proteins are found in different cells. The most specific markers of astrocytes are gfap and s100β.